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Image Search Results
Journal: The Journal of Neuroscience
Article Title: Representations of Time-Varying Cochlear Implant Stimulation in Auditory Cortex of Awake Marmosets ( Callithrix jacchus )
doi: 10.1523/JNEUROSCI.0093-17.2017
Figure Lengend Snippet: CI stimulus artifact removal. Electrical artifacts caused by CI stimulation were removed from neural recordings using a notch filter. a, Electrical artifacts were typically an order of magnitude larger than spiking activity. Raw neural signal was recorded during a 500 ms duration; 488 Hz stimulus is shown. Without artifact removal, such high stimulation rates prevent reliable sorting during the stimulus period. b, Frequency spectrum of the raw signal shown in a. Spectral peaks occur at integer multiples of the stimulus repetition rate. c, A notch filter was created with spectral nulls at integer multiples of the stimulus repetition rate. d, The raw signal was digitally filtered with the notch filter, allowing spikes to be recovered. e, Spikes were sorted offline using a custom template-based sorting MATLAB program. Spikes obtained after filtering were reduced in amplitude (black), but maintained similar shape as unfiltered spikes (gray). f, SNR of isolated units was large enough to very reliably sort units after notch filtering (median = 28.1 dB). g, Neural responses to CI stimulus delivered at 4–488 Hz. Only responses to stimuli ≥128 Hz were notch filtered. For visualization, stimulus artifact in unfiltered signals is highlighted red.
Article Snippet: Without artifact removal, such high stimulation rates prevent reliable sorting during the stimulus period. b , Frequency spectrum of the raw signal shown in a . Spectral peaks occur at integer multiples of the stimulus repetition rate. c , A notch filter was created with spectral nulls at integer multiples of the stimulus repetition rate. d , The raw signal was digitally filtered with the notch filter, allowing spikes to be recovered. e , Spikes were sorted offline using a
Techniques: Activity Assay, Isolation